|  Help  |  About  |  Contact Us

Allele : Igh<tm1.1(Igh564)Tik> immunoglobulin heavy chain complex; targeted mutation 1.1, Thereza Imanishi-Kari

Primary Identifier  MGI:3687305 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Igh
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin resistance gene, as well as the VDJ 564 region from a hybridoma derived from an autoimmune SWRxNZB mouse, replaced a segment of DNA including DQ52 and the entire JH region. Male chimeric mice were bred to C57BL/6 females. The resulting offspring were crossed with cre expressing transgenic mice in order to excise the neomycin resistance cassette. (personal communication)
  • mutations:
  • Insertion
  • synonyms:
  • IgH564,
  • IgH564
Quick Links:
 
Quick Links:
 

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

15 Publication categories