Primary Identifier | MGI:5911664 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Tifab |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 3 which encodes the protein coding region was replaced with a beta- galactosidase cassette and a floxed neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. Immunoblot analysis confirmed the absence of protein expression in bone marrow lysates from homozygous mice. |