| Primary Identifier | MGI:1919989 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 72739 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within autophagy. Predicted to be located in cytoplasm and nucleoplasm. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and retina nuclear layer. Orthologous to human ZKSCAN3 (zinc finger with KRAB and SCAN domains 3) and ZKSCAN4 (zinc finger with KRAB and SCAN domains 4). PHENOTYPE: Mice homozygous for a null allele exhibit normal weight, size, appearance and autophagy response to starvation and re-feeding. Mice homozygous for a different null allele exhibit increased P. aeruginosa strain K killing in the lungs. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
