Primary Identifier | MGI:6099055 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Gata1 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting vector is designed to replace exon 2 with a loxP-flanked neomycin resistance (neo) cassette. The neo cassette was deleted by transiently transfection of an expression vector of Cre recombinase in the ES cells. The resulting protein GATAs is truncated. |