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Allele : Fos<tm5.1Wag> FBJ osteosarcoma oncogene; targeted mutation 5.1, Erwin F Wagner

Primary Identifier  MGI:5142240 Allele Type  Targeted
Attribute String  Reporter Gene  Fos
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 4 was replaced with a modified exon in which nucleotide substitutions result in the amino acid substitution of alanine for serine at positions 362 and 374 (S362A and S374A). Flp-mediated recombination removed the floxed neo cassette inserted downstream of the endogenous polyadenylation sequence and left an EGFP gene with a 5' loxP site intact.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • FosAA,
  • FosAA,
  • c-fos<AA>,
  • c-fos<AA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele