| Primary Identifier | MGI:98497 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 21391 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables thromboxane-A synthase activity. Predicted to be involved in intracellular chloride ion homeostasis; positive regulation of vasoconstriction; and prostaglandin biosynthetic process. Predicted to act upstream of or within fatty acid biosynthetic process and prostaglandin metabolic process. Predicted to be located in cytosol and endoplasmic reticulum membrane. Is expressed in several structures, including bone marrow; brain; liver; lung; and metanephros. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome and cerebral infarction. Orthologous to human TBXAS1 (thromboxane A synthase 1). PHENOTYPE: Homozygous null mice display increased bleeding time and decreased platelet response to arachidonic acid. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
