| Type | MGI:General | Description | homozygotes are more susceptible to a low inoculum (i.v., 105 cells) of the CA-6 strain of C. albicans, with ~88% homozygotes dying within 14 days while all wild-type mice survive both wild-type and mutant mice survive challenge with 106 cells of the low virulence PCA-2 strain; however, unlike wild-type mice, homozygotes fail to survive a subsequent lethal CA-6 challenge, with a high number of C. albicans cells found in the kidney increased susceptibility to C. albicans infection is associated with predominance of a Th2-type response |
