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Protein Coding Gene : Spon1 spondin 1, (f-spondin) extracellular matrix protein
Primary Identifier  MGI:2385287 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  233744
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables LBD domain binding activity. Acts upstream of or within negative regulation of amyloid-beta formation; positive regulation of amyloid precursor protein catabolic process; and positive regulation of protein processing. Located in collagen-containing extracellular matrix. Is expressed in several structures, including aorta; craniocervical region bone; nervous system; palatal shelf; and sensory organ. Orthologous to human SPON1 (spondin 1).
PHENOTYPE: Mice homozygous for a null allele display increased trabecular and cortical bone mass. [provided by MGI curators]
  • synonyms:
  • cDNA sequence BC020531,
  • RIKEN cDNA D330035F22 gene,
  • BC020531,
  • AW455831,
  • Spon1,
  • D330035F22Rik,
  • MGI:2142024,
  • AI666765,
  • spondin 1, (f-spondin) extracellular matrix protein,
  • expressed sequence AW455831,
  • MGI:2142230,
  • FSP,
  • expressed sequence AI666765
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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1 Driver For

Trail: ProteinCodingGene




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