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Protein Coding Gene : Actl6a actin-like 6A

Primary Identifier  MGI:1861453 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  56456
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables chromatin binding activity. Involved in several processes, including positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Acts upstream of or within blastocyst formation and chromatin remodeling. Located in nucleus. Part of SWI/SNF complex and npBAF complex. Is expressed in several structures, including central nervous system; genitourinary system; lung; nose; and tooth. Orthologous to human ACTL6A (actin like 6A).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality before E6.5. Mice homozygous for a conditional allele activated in hematopoietic cells exhibit bone marrow failure and premature death. [provided by MGI curators]
  • synonyms:
  • Baf53a,
  • MGI:1919992,
  • Actl6a,
  • actin-like 6A,
  • MGI:2140068,
  • expressed sequence C79802,
  • C79802,
  • MGI:2139823,
  • expressed sequence AI851094,
  • ARP4,
  • 2810432C06Rik,
  • AI851094,
  • RIKEN cDNA 2810432C06 gene,
  • Actl6

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

16 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For