Primary Identifier | MGI:1929693 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 56857 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable glucose 6-phosphate:phosphate antiporter activity and glycerol-3-phosphate transmembrane transporter activity. Predicted to be involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Predicted to act upstream of or within glycerol-3-phosphate metabolic process; glycerol-3-phosphate transmembrane transport; and glycerophosphate shuttle. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human SLC37A2 (solute carrier family 37 member 2). PHENOTYPE: Mice homozygous for a null allele exhibit increased pro-inflammatory cytokine production and accelerated glycolysis and mitochondrial oxidation in macrophages. [provided by MGI curators] |