| Primary Identifier | MGI:1920336 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 73086 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables ATP binding activity and protein serine/threonine kinase activity. Involved in intracellular signal transduction; regulation of DNA-templated transcription; and regulation of postsynapse organization. Located in nucleus. Orthologous to human RPS6KA5 (ribosomal protein S6 kinase A5). PHENOTYPE: Mice homozygous for a mutant allele exhibit altered response to cocaine including decreased hyperlocomotor activity and sensitization at a lower dose. Mice homozygous for a kinase dead allele exhibit altered experience-dependent synaptic plasticity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
