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Protein Coding Gene : Eif2s2 eukaryotic translation initiation factor 2 subunit 2 beta
Primary Identifier  MGI:1914454 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  67204
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable mRNA binding activity; translation initiation factor activity; and translation initiation factor binding activity. Acts upstream of or within in utero embryonic development; male germ cell proliferation; and male gonad development. Is active in synapse. Is expressed in several structures, including blastocyst; colon; early embryo; gonad; and liver. Orthologous to human EIF2S2 (eukaryotic translation initiation factor 2 subunit beta).
PHENOTYPE: Mice homozygous for a gene trap allele exhibit embryonic lethallity prior to E8.5. Mice heterozygous for a gene trap allele exhibit reduced incidence of testicular germ cell tumors. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2810026E11 gene,
  • expressed sequence AA571381,
  • Eif2s2,
  • AA408636,
  • expressed sequence AW822225,
  • AW822225,
  • D2Ertd303e,
  • AA986487,
  • MGI:2138820,
  • MGI:2138795,
  • AA571381,
  • DNA segment, Chr 2, ERATO Doi 303, expressed,
  • expressed sequence AA986487,
  • MGI:2139418,
  • EIF2B,
  • 2810026E11Rik,
  • MGI:1098790,
  • EIF2,
  • expressed sequence AA408636,
  • 38kDa,
  • eukaryotic translation initiation factor 2 subunit 2 beta,
  • MGI:2138753
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