Primary Identifier | MGI:1927804 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Nrp2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The insertion of the pGT1.8TM secretory trap vector, containing a beta galactosidase reporter gene, occurred in an intron interrupting the neuropilin-2 coding sequence at cDNA position 2069 nt (amino acid Pro-680). The insertion site is located one-third of the way into the MAM domain of neuropilin-2. This mutation appears to be a loss of function. |