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Publication : Kinin receptors.

First Author  Marceau F Year  1998
Journal  Clin Rev Allergy Immunol Volume  16
Issue  4 Pages  385-401
PubMed ID  9926287 Mgi Jnum  J:52489
Mgi Id  MGI:1329550 Doi  10.1007/BF02737658
Citation  Marceau F, et al. (1998) Kinin receptors. Clin Rev Allergy Immunol 16(4):385-401
abstractText  Rapid developments are expected in the molecular pharmacology of both B1, and B2 types of kinin receptors, since the underlying genetic structures are now known and widely studied. The consequences of kinin receptor duality and physiopathological regulation have not yet been fully appreciated. Medicinal chemistry is also an active front of research in kinin pharmacology, as more effective drugs targeted at kinin receptors are regularly reported. Various complementary molecular approaches (the receptor binding, cloning, immunoreacting, mutagenesis, inactivation, the study of regulation, allelic polymorphisms, and so forth) are expanding our knowledge of the role of kinins in allergy, inflammation, and singularly, renal medicine.
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