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Protein Domain : SepF-like superfamily

Primary Identifier  IPR038594 Type  Homologous_superfamily
Short Name  SepF-like_sf
description  This entry represents a cell division protein, designated SepF, which is conserved in Gram-positive bacteria. SepF accumulates at the cell division site in an FtsZ-dependent manner and is required for proper septum formation [, ]. This protein uses an amphipathic helix for membrane binding and polymerises into large rings that bundle FtsZ filaments []. Mutants are viable but the formation of the septum is much slower and occurs with a very abnormal morphology. This entry also includes archaeal related proteins, such as SepF from Haloferax volcanii [].

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