| Primary Identifier | MGI:3815201 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Cbfa2t3 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Cbfa2t3tm1Swh heterozygotes were crossed with transgenic cre mice resulting in excision of exon 8 from the germline. It was predicted to be a null allele because splicing from exon 7 to exon 9 introduces a stop codon and would trigger nonsense-mediated mRNA decay. Gene inactivation in homozygotes was confirmed by a lack of signal in immunoblot assays of splenocyte nuclear extracts. |
