| Primary Identifier | MGI:93882 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 434215 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables transforming growth factor beta binding activity. Involved in regulation of transforming growth factor beta3 activation and secondary palate development. Acts upstream of or within negative regulation of activated T cell proliferation; negative regulation of cytokine production; and positive regulation of gene expression. Predicted to be located in cell surface and nucleoplasm. Predicted to be active in external side of plasma membrane; extracellular matrix; and extracellular space. Is expressed in several structures, including genitourinary system; jaw; lung; sensory organ; and skeletal muscle. Orthologous to human LRRC32 (leucine rich repeat containing 32). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete neonatal lethality and defective secondary palate development with no apparent abnormalities in other major organs. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
