| First Author | Feng J | Year | 1996 |
| Journal | Genome Res | Volume | 6 |
| Issue | 10 | Pages | 956-64 |
| PubMed ID | 8908514 | Mgi Jnum | J:36276 |
| Mgi Id | MGI:83742 | Doi | 10.1101/gr.6.10.956 |
| Citation | Feng J, et al. (1996) Bovine natural resistance associated macrophage protein 1 (Nramp1) gene. Genome Res 6(10):956-64 |
| abstractText | The Bcg/Ity/Lsh locus is a major gene controlling early phases of infection with intracellular parasites in mice. Natural resistance associated macrophage protein 1 (Nramp1) has been shown to be the Bcg gene in mice. Analysis of a bovine cDNA homolog of murine Nramp1, designated as bovine NRAMP1, predicted a 548-amino-acid protein with hydrophobic domains, an amino-terminal SH3-binding domain, and a conserved consensus transport motif. Northern blotting indicated that bovine NRAMP1 was expressed primarily in macrophages and tissues of the recticuloendothelial system. Bovine NRAMP1 was mapped to BTA 2 within syntenic loci conserved on HSA 2q and MMU 1. |
