Primary Identifier | MGI:107166 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 22355 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable G protein-coupled peptide receptor activity; peptide hormone binding activity; and vasoactive intestinal polypeptide receptor activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway and negative regulation of smooth muscle cell proliferation. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; respiratory system; retina; and skeleton. Orthologous to human VIPR2 (vasoactive intestinal peptide receptor 2). PHENOTYPE: Homozygotes for a targeted null mutation exhibit enhanced delayed-type hypersensitivity (type IV) and reduced immediate-type hypersensitivity (type I). [provided by MGI curators] |