| Primary Identifier | IPR024087 | Type | Homologous_superfamily |
| Short Name | Creatininase-like_sf |
| description | Creatinase () catalyses the hydrolysis of creatinine to creatine, which can then be metabolised to urea and sarcosine by creatinase. Formamide hydrolase catalyzes the hydrolysis of the formamide of 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy) ().Creatininase from Pseudomonas putida has a structure consisting of 3-layers, alpha/beta/alpha, where the core consists of a parallel β-sheet of 4 strands. The enzyme is a typical Zn2+ enzyme with a binuclear metal centre [].This superfamily represents the structural domain found in creatininases and in formamide hydrolases. |
