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Allele : Cdkn2a<tm1Cjs> cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr

Primary Identifier  MGI:1926877 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Cdkn2a
Inheritance Mode  Recessive Transmission  Germline
Strain of Origin  129X1/SvJ Is Recombinase  false
Is Wild Type  false
molecularNote  Replacement of exon 1 beta of the Cdkn2a gene, encoding the translation start site for alternative splice transcript p19ARF, with a neomycin cassette. Note that expression of alternative splice transcript p16Ink4a, transcribed from exon 1 alpha, is not affected by this mutation.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • p19<Arf>-null,
  • ARF-,
  • p19<Arf>-null,
  • p19<ARF->,
  • ARF-,
  • p19Arf<->,
  • p19<ARF->,
  • p19Arf<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

6 Carried By

Trail: Allele

0 Driven By

165 Publication categories

Trail: Allele