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Allele : Kit<W-sh> KIT proto-oncogene receptor tyrosine kinase; sash

Primary Identifier  MGI:1856265 Allele Type  Spontaneous
Gene  Kit Inheritance Mode  Semidominant
Strain of Origin  (C3H/HeH x 101/H)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The molecular mutation of this allele is an inversion located proximal to the Kit structural gene that disrupts 5' regulatory sequences. Transcripts were not detectable from this allele in cultured mast cells derived from homozygous mice. However, an analysis of embryonic expression revealed that ectopic expression of Kit occurred in homozygous mice and normal expression was ablated.
  • mutations:
  • Inversion
  • synonyms:
  • Sash,
  • W-sh,
  • Wsh,
  • W-sh,
  • c-Kit<wsh>,
  • W<sh>,
  • Sash,
  • W<sh>,
  • Wsh,
  • c-Kit<wsh>
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1 Feature

Trail: Allele

Genome

0 Expresses

32 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

19 Carried By

Trail: Allele

0 Driven By

327 Publication categories

Trail: Allele