| Primary Identifier | MGI:1914723 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 67473 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables polyspecific organic cation:proton antiporter activity. Involved in monoatomic cation transmembrane transport and xenobiotic transmembrane transport. Located in plasma membrane. Is expressed in several structures, including liver; lung; metanephros; nervous system; and spleen. Orthologous to several human genes including SLC47A1 (solute carrier family 47 member 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased blood urea nitrogen, increased circulating creatinine, and abnormal metformin pahrmacokinetics including increased plasma and tissue concentration with decreased kidney and liver clearance. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
