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Allele : Ptpn11<tm1Rbn> protein tyrosine phosphatase, non-receptor type 11; targeted mutation 1, Daniel U Rabin

Primary Identifier  MGI:2176526 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptpn11
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
description  ES cell line = G1 (Bayer Corp., unpublished). This appears to have been derived from an unspecified subline of 129.
molecularNote  A neomycin resistance cassette replaced a genomic fragment containing exon 2 and flanking sequences. Western blot analysis on lyastes prepared from various tissues of heterozygous mice confirmed that protein levels were reduced by 40-50% in all tissue examined.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • syp,
  • syp
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele