First Author | Gayle MA | Year | 1996 |
Journal | J Biol Chem | Volume | 271 |
Issue | 10 | Pages | 5784-9 |
PubMed ID | 8621446 | Mgi Jnum | J:31857 |
Mgi Id | MGI:79360 | Doi | 10.1074/jbc.271.10.5784 |
Citation | Gayle MA, et al. (1996) Cloning of a putative ligand for the T1/ST2 receptor. J Biol Chem 271(10):5784-9 |
abstractText | T1/ST2 is a receptor-like molecule homologous to the type I interleukin-1 receptor. Despite this sequence similarity, we have been unable to demonstrate binding of T1/ST2 to any of the three interleukin-1 species. In searching for a ligand for T1/ST2, we have cloned a cell surface protein to which it binds. This protein is unable to initiate signal transduction by the T1/ST2 receptor in several in vitro assays. |