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Publication : Cloning of a putative ligand for the T1/ST2 receptor.

First Author  Gayle MA Year  1996
Journal  J Biol Chem Volume  271
Issue  10 Pages  5784-9
PubMed ID  8621446 Mgi Jnum  J:31857
Mgi Id  MGI:79360 Doi  10.1074/jbc.271.10.5784
Citation  Gayle MA, et al. (1996) Cloning of a putative ligand for the T1/ST2 receptor. J Biol Chem 271(10):5784-9
abstractText  T1/ST2 is a receptor-like molecule homologous to the type I interleukin-1 receptor. Despite this sequence similarity, we have been unable to demonstrate binding of T1/ST2 to any of the three interleukin-1 species. In searching for a ligand for T1/ST2, we have cloned a cell surface protein to which it binds. This protein is unable to initiate signal transduction by the T1/ST2 receptor in several in vitro assays.
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