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Allele : Myd88<tm1Aki> myeloid differentiation primary response gene 88; targeted mutation 1, Shizuo Akira

Primary Identifier  MGI:2385681 Allele Type  Targeted
Attribute String  Null/knockout Gene  Myd88
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a 1.0 kb genomic fragment that contained sequences encoding the C-terminal cytoplasmic domain of the protein. Northern blot analysis confirmed that the encoded mRNA could not be detected in the liver and spleen of homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • MyD88 KO,
  • MyD88 KO,
  • MyD88-,
  • MyD88-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

10 Carried By

Trail: Allele

0 Driven By

1318 Publication categories

Trail: Allele