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Protein Coding Gene : Wnt8b wingless-type MMTV integration site family, member 8B

Primary Identifier  MGI:109485 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  22423
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within negative regulation of gene expression and positive regulation of gene expression. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cochlea; eye; future brain; head mesenchyme; and nervous system. Human ortholog(s) of this gene implicated in Hirschsprung's disease. Orthologous to human WNT8B (Wnt family member 8B).
PHENOTYPE: Mice homozygous for a null allele are viable and healthy with no evidence of hippocampal or hypothalamic defects and normal cell proliferation in the neurogenic region of the adult dentate gyrus. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-39484,
  • wingless-type MMTV integration site family, member 8B,
  • Wnt8b

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For