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Protein Coding Gene : Adgrl2 adhesion G protein-coupled receptor L2

Primary Identifier  MGI:2139714 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  99633
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable G protein-coupled receptor activity and PDZ domain binding activity. Involved in synapse organization. Acts upstream of or within positive regulation of synapse assembly and response to bacterium. Is active in glutamatergic synapse and postsynaptic membrane. Is expressed in cerebellum; heart; spinal cord dorsal horn; and spinal cord lumbar region. Orthologous to human ADGRL2 (adhesion G protein-coupled receptor L2).
PHENOTYPE: Homozygous null mice die prenatally at fetal stages with cardiac defects. Heterozygous mice exhibit decreased locomotor activity in an open field test. [provided by MGI curators]
  • synonyms:
  • AI450192,
  • latrophilin 2,
  • latrophilin 1,
  • Lphh1,
  • Adgrl2,
  • Lphn2,
  • Lec1,
  • mKIAA0786,
  • expressed sequence AI450192,
  • adhesion G protein-coupled receptor L2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For