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Protein Coding Gene : Cops2 COP9 signalosome subunit 2

Primary Identifier  MGI:1330276 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  12848
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables transcription corepressor activity. Acts upstream of or within blastocyst growth; negative regulation of DNA-templated transcription; and skeletal muscle cell differentiation. Located in nucleus. Part of COP9 signalosome. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human COPS2 (COP9 signalosome subunit 2).
PHENOTYPE: Mice homozygous for disruptions in this gene die as embryos very soon after implantation. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI315723,
  • MGI:2138892,
  • Sgn2,
  • Trip15,
  • C85265,
  • alien homologue,
  • Csn2,
  • Cops2,
  • alien-like,
  • MGI:2139517,
  • AI315723,
  • expressed sequence C85265,
  • COP9 signalosome subunit 2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

19 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For