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Protein Coding Gene : Esyt2 extended synaptotagmin-like protein 2
Primary Identifier  MGI:1261845 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  52635
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable calcium ion binding activity; identical protein binding activity; and phospholipid binding activity. Predicted to be involved in endoplasmic reticulum-plasma membrane tethering and lipid transport. Predicted to act upstream of or within endocytosis. Predicted to be located in cytoplasmic side of plasma membrane; cytosol; and endoplasmic reticulum-plasma membrane contact site. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including aorta; genitourinary system; mammary gland; nervous system; and retina. Orthologous to human ESYT2 (extended synaptotagmin 2).
PHENOTYPE: Mice are viable and fertile without overt morphological defects except reduced FGF-stimulated mouse embryonic fibroblast migration. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2310058N22 gene,
  • DNA segment, Chr 12, ERATO Doi 551, expressed,
  • RIKEN cDNA 4921504I16 gene,
  • family with sequence similarity 62 (C2 domain containing), member B,
  • Esyt2,
  • D12Ertd551e,
  • MGI:1919171,
  • RIKEN cDNA 2410017M09 gene,
  • MGI:1921297,
  • 2410017M09Rik,
  • MGI:1919208,
  • Fam62b,
  • extended synaptotagmin-like protein 2,
  • 2310058N22Rik,
  • 4921504I16Rik
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