| Primary Identifier | IPR026829 | Type | Family |
| Short Name | Mon2-like |
| description | Monensin-resistant homologue 2 (Mon2) is a peripheral membrane protein involved in multiple aspects of endomembrane trafficking [, ]. In Drosophila it has been described to couple endocytosis with actin remodeling []. In budding yeast, Mon2 plays a role in endocytosis and maintenance of vacuolar structure [, ]. Mon2 is distantly related to the guanine nucleotide exchange factors (GEFs) that activate Arf1 on Golgi membranes. However, Mon2 lacks the Sec7 domain that catalyses nucleotide exchange on Arf1 []. In Drosophila it has been described to couple endocytosis with actin remodeling []. |
