Primary Identifier | MGI:5553453 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Lrig2 |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 12. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 12. Cre-mediated recombination removed exon 12 and the resistance cassette. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts. |