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Allele : Tshr<hyt-2J> thyroid stimulating hormone receptor; hypothyroid 2 Jackson

Primary Identifier  MGI:4453218 Allele Type  Spontaneous
Attribute String  Not Specified Gene  Tshr
Inheritance Mode  Recessive Strain of Origin  (C57BL/6J-A<w-J> x 129P3/J)F2/J
Is Recombinase  false Is Wild Type  false
molecularNote  This spontaneous C-to-T transition in chromosome 12 position 91,537,844 bp (GRCm38) causes a premature stop codon in exon 10 at arginine 519 (p.R519*), resulting in a loss of at least the transmembrane portion of the encoded protein.
  • mutations:
  • Single point mutation
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele