Primary Identifier | MGI:4453218 | Allele Type | Spontaneous |
Attribute String | Not Specified | Gene | Tshr |
Inheritance Mode | Recessive | Strain of Origin | (C57BL/6J-A<w-J> x 129P3/J)F2/J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This spontaneous C-to-T transition in chromosome 12 position 91,537,844 bp (GRCm38) causes a premature stop codon in exon 10 at arginine 519 (p.R519*), resulting in a loss of at least the transmembrane portion of the encoded protein. |