| First Author | Nawa G | Year | 1998 |
| Journal | J Hum Genet | Volume | 43 |
| Issue | 4 | Pages | 262-7 |
| PubMed ID | 9852680 | Mgi Jnum | J:51784 |
| Mgi Id | MGI:1326857 | Doi | 10.1007/s100380050086 |
| Citation | Nawa G, et al. (1998) Cloning and characterization of the murine P2XM receptor gene. J Hum Genet 43(4):262-7 |
| abstractText | We have isolated the murine counterpart of the human P2XM gene (mP2XM), a P2X purinoceptor that is expressed predominantly in skeletal muscle. The mP2XM gene, consisting of 12 exons that span 10 kb of genomic DNA, encodes a 379-amino-acid product with 83% identity to the human homologue. Two potential transmembrane domains (M1 and M2) are present in the predicted product, and a segment resembling the H5 region of voltage-gated ion channels is completely conserved between human and mouse P2XM proteins. Predominant expression of mP2XM in murine skeletal muscle was confirmed by Northern-blot analysis, and a low level of expression was detectable in lung tissue, although human lung does not express P2XM. |
