Primary Identifier | MGI:2655562 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 170757 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and protein-containing complex assembly. Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasmic vesicle. Predicted to be active in plasma membrane. Is expressed in cardiovascular system; lung; metanephros; and skeletal muscle. Orthologous to human ADGRL4 (adhesion G protein-coupled receptor L4). PHENOTYPE: Mice homozygous for a null allele exhibit increased vessel perfusion within injected tumors with reduced vascular permeability and reduced tumor hypoxia . [provided by MGI curators] |