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Allele : Ripk1<em2Jhan> receptor (TNFRSF)-interacting serine-threonine kinase 1; endonuclease-mediated mutation 2, Jiahuai Han

Primary Identifier  MGI:7258412 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Ripk1
Is Recombinase  false Is Wild Type  false
molecularNote  Using an sgRNA (targeting CCCGAAGCCTCCGCTGTCT) and an ssODN template with CRISPR/Cas9 technology, a 6 bp sequence was deleted (c.81_86delCTTCGG), resulting in the deletion of two highly conserved amino acids, F28 and G29, from the P-loop of the N-terminal kinase domain of the encoded protein.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Ripk1<delta>,
  • Ripk1<delta>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele