Primary Identifier | MGI:2138069 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 94353 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables chromatin binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II and regulation of insulin secretion involved in cellular response to glucose stimulus. Located in nucleus. Is expressed in several structures, including central nervous system; epithelium; eye; genitourinary system; and limb. Orthologous to human HMGN3 (high mobility group nucleosomal binding domain 3). PHENOTYPE: Mice homozygous for a null allele exhibit impaired glucose tolerance with decreased insulin serum levels and increased glucose serum levels during feeding. [provided by MGI curators] |