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Protein Coding Gene : Hmgn3 high mobility group nucleosomal binding domain 3

Primary Identifier  MGI:2138069 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  94353
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables chromatin binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II and regulation of insulin secretion involved in cellular response to glucose stimulus. Located in nucleus. Is expressed in several structures, including central nervous system; epithelium; eye; genitourinary system; and limb. Orthologous to human HMGN3 (high mobility group nucleosomal binding domain 3).
PHENOTYPE: Mice homozygous for a null allele exhibit impaired glucose tolerance with decreased insulin serum levels and increased glucose serum levels during feeding. [provided by MGI curators]
  • synonyms:
  • MGI:2143355,
  • 1110002A15Rik,
  • RIKEN cDNA 6330514M13 gene,
  • TRIP7,
  • expressed sequence BB071015,
  • HMGN3b,
  • MGI:1914636,
  • high mobility group nucleosomal binding domain 3,
  • Hmgn3,
  • BB071015,
  • HMGN3a,
  • 6330514M13Rik,
  • RIKEN cDNA 1110002A15 gene,
  • MGI:1923404

Features --> Cross References

Genome

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1 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

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Disease

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