| Primary Identifier | MGI:1914362 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 67112 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable fibroblast growth factor receptor binding activity and growth factor activity. Predicted to be involved in several processes, including fibroblast growth factor receptor signaling pathway; positive regulation of cell population proliferation; and positive regulation of macromolecule metabolic process. Located in Golgi apparatus; cell surface; and nucleolus. Is expressed in brain; early conceptus; gonad; spinal cord; and tongue. Orthologous to human FGF22 (fibroblast growth factor 22). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired vesicle clustering in glutamatergic synapses, decreased miniature excitatory postsynaptic currents, enhanced paired-pulse facilitation, increased synaptic depression, and decreased susceptibility topentylenetetrazol-induced seizures. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
