| Primary Identifier | MGI:95518 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 14175 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable fibroblast growth factor receptor binding activity and growth factor activity. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; positive regulation of macromolecule metabolic process; and skeletal system morphogenesis. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including branchial pouch; cerebellum; embryo mesenchyme; surface ectoderm; and tooth. Orthologous to human FGF4 (fibroblast growth factor 4). PHENOTYPE: Embryos homozygous for a knock-out allele undergo implantation but degenerate shortly thereafter. In vitro, cultured embryos show severely impaired proliferation of the inner cell mass. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
