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Allele : Setdb2<tm1Desr> SET domain, bifurcated 2; targeted mutation 1, David E Symer
Primary Identifier  MGI:5751798 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph Gene  Setdb2
Transmission  Germline Strain of Origin  (C57BL/6J x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A gene trap (containing an FRT site, loxP site, pGK/EM7 dual promoter, strong splice acceptor from En2, neomycin resistance cassette, polyadenylation sequence, FRT site and loxP) was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 3. Western blot analysis confirmed reduced protein expression in the spleen, lung and bone marrow-derived macrophages.
  • mutations:
  • Insertion,
  • Insertion of gene trap vector
  • synonyms:
  • Setdb2<GT>,
  • Setdb2<GT>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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2 Carried By

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0 Driven By

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Trail: Allele




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