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Publication : Centromere-linkage analysis and consolidation of the zebrafish genetic map.

First Author  Johnson SL Year  1996
Journal  Genetics Volume  142
Issue  4 Pages  1277-88
PubMed ID  8846904 Mgi Jnum  J:32210
Mgi Id  MGI:79705 Doi  10.1093/genetics/142.4.1277
Citation  Johnson SL, et al. (1996) Centromere-linkage analysis and consolidation of the zebrafish genetic map. Genetics 142(4):1277-88
abstractText  The ease of isolating mutations in zebrafish will contribute to an understanding of a variety of processes common to all vertebrates. To facilitate genetic analysis of such mutations, we have identified DNA polymorphisms closely linked to each of the 25 centromeres of zebrafish, placed centromeres on the linkage map, increased the number of mapped PCR-based markers to 652, and consolidated the number of linkage groups to the number of chromosomes. This work makes possible centromere-linkage analysis, a novel, rapid method to assign mutations to a specific linkage group using half-tetrads.
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