Primary Identifier | MGI:4838422 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Stk39 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | One loxP site was inserted just 5' of exon 9 and an FRT flanked neomycin selection cassette was placed in intron 10 followed by a second loxP site. The selection cassette was subsequently excised from properly targeted ES cells usin flp recombinase, leaving exons 9 and 10 flanked by loxP sites. Mice were then crossed to transgenic mice expressing Tg(CAG-cre)13Miya to delete exons 9 and 10. |