Primary Identifier | MGI:5296847 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Itgb1 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed neo cassette was inserted downstream of a modified exon 16 in which nucleotide substitutions result in the amino acid substitutions of alanine for tyrosine at positions 783 and 795 (Y783A and Y795A). Cre-mediated recombination removed the neo cassette. |