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Protein Coding Gene : Cxcl1 C-X-C motif chemokine ligand 1

Primary Identifier  MGI:108068 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  14825
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable CXCR chemokine receptor binding activity and chemokine activity. Involved in several processes, including positive regulation of hematopoietic stem cell proliferation; positive regulation of neutrophil mediated killing of fungus; and positive regulation of superoxide anion generation. Located in extracellular space. Is expressed in several structures, including arterial system; liver; nervous system; retina; and small intestine. Orthologous to human CXCL1 (C-X-C motif chemokine ligand 1) and CXCL2 (C-X-C motif chemokine ligand 2).
PHENOTYPE: Targeted mutations in this gene when combine with targeted mutation of Ldlr decreases susceptibility to atherosclerotic lesions. [provided by MGI curators]
  • synonyms:
  • melanoma growth stimulatory activity,
  • MGD-MRK-12226,
  • Cxcl1,
  • fibroblast secretory protein,
  • Fsp,
  • MGD-MRK-37105,
  • Scyb1,
  • MGD-MRK-9878,
  • GRO1 oncogene,
  • C-X-C motif chemokine ligand 1,
  • Gro1,
  • N51,
  • Mgsa,
  • KC,
  • KC/GRO-alpha

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

11 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For