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Allele : P4ha2<tm1Jomy> procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide; targeted mutation 1, Johanna Myllyharju

Primary Identifier	MGI:5645507	Allele Type	Targeted
Attribute String	Null/knockout	Gene	P4ha2
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

A lacZ-PKG-neo cassette inserted in-frame into the third exon of the gene after the translation initiation codon via homologous recombination.

mutations:
Insertion

cellLines:
Not Specified

earliestPublication:
Aro E, et al. (2015) Severe Extracellular Matrix Abnormalities and Chondrodysplasia in Mice Lacking Collagen Prolyl 4-Hydroxylase Isoenzyme II in Combination with a Reduced Amount of Isoenzyme I. J Biol Chem 290(27):16964-78

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele

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MouseMine

Allele : P4ha2<tm1Jomy> procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide; targeted mutation 1, Johanna Myllyharju

External Links

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

5 Publication categories