| First Author | Nishioka Y | Year | 1992 |
| Journal | Genetica | Volume | 87 |
| Issue | 1 | Pages | 7-15 |
| PubMed ID | 1459466 | Mgi Jnum | J:3332 |
| Mgi Id | MGI:51845 | Doi | 10.1007/BF00128768 |
| Citation | Nishioka Y, et al. (1992) Nucleotide sequence analysis of a mouse Y chromosomal DNA fragment containing Bkm and LINE elements. Genetica 87(1):7-15 |
| abstractText | The strong suppression of crossing-over between the X and Y chromosomes permits rapid accumulation of repetitive sequences in the Y chromosome. To gain insight into the mechanism responsible for the sequence amplification, it is essential to characterize Y chromosomal repetitive sequences at the molecular level. Here, we report the entire nucleotide sequence (3,902bp) of AC11, a mouse sequence that is repeated 300 times in the Y chromosome. AC11 is AT rich (32.8% GC), and contains many short poly(A) sequences. In addition, it has Bkm and LINE sequences as well as a Y chromosome-specific sequence. The Bkm sequence consists of typical (GATA) and (GACA) repeating units, whereas the LINE sequence deviates considerably from other mouse LINE sequences (71-76% identity) and may be considered atypical. The Y chromosome-specific region seems to be unique and does not identify similar sequences in the GenBank library. The information obtained from the nucleotide sequence should form the foundation to study the evolutionary processes through which AC11-related sequences have accumulated in the mouse Y chromosome. |
