Type | MGI:General | Description | amount of polymerized F-actin in cardiomyocytes progressively decreases after tamoxifen treatment myofibrils at the intercalated disks are often stretched and fragmented following tamoxifen treatment Z disks of cardiomyocytes are misaligned and myofibrils are split 60 days after tamoxifen treatment 60 days after tamoxifen treatment, cardiac tissue shows a lower density of myofibrils and a defect in demarcation of Z lines and M lines |