First Author | Meruelo D | Year | 1977 |
Journal | J Exp Med | Volume | 146 |
Issue | 4 | Pages | 1088-95 |
PubMed ID | 197196 | Mgi Jnum | J:5864 |
Mgi Id | MGI:54341 | Doi | 10.1084/jem.146.4.1088 |
Citation | Meruelo D, et al. (1977) Genetic control of radiation leukemia virus-induced tumorigenesis II. Influence of Srlv-1, a locus not linked to H-2. J Exp Med 146(4):1088-95 |
abstractText | A single locus, tentatively denoted Srlv-1 (susceptibility to radiation leukemia virus [RadLV]-1), confers dominant susceptibility to RadLV-induced leukemogenesis. Srlv-1 is not linked to H-2, and appears to be distinct from Fv-1 and Fv-2. Preliminary data suggest that Srlv-1 affected virus proliferation. A striking feature of this system is that Srlv-1 overrides the protection afforded by the H2D-associated dominant resistance to RadLV-induced neoplasia. |