| First Author | Johnson TL | Year | 1991 |
| Journal | Genomics | Volume | 11 |
| Issue | 3 | Pages | 770-2 |
| PubMed ID | 1774075 | Mgi Jnum | J:11586 |
| Mgi Id | MGI:59997 | Doi | 10.1016/0888-7543(91)90089-w |
| Citation | Johnson TL, et al. (1991) Chromosomal assignment in mouse of matrix Gla protein and bone Gla protein genes. Genomics 11(3):770-2 |
| abstractText | Matrix Gla protein (MGLAP) and bone Gla protein (BGLAP) are calcium-binding, vitamin K-dependent proteins produced by cells of the osteoblastic lineage. Sequence homology suggests that the genes for these proteins evolved from a common ancestor. Somatic whole cell hybrids and karyotypically simple microcell hybrids were used to map Mglap to mouse Chromosome 6 and Bglap to mouse Chromosome 3. Human MGLAP has previously been mapped to chromosome 12p, a region with homology to mouse Chromosome 6, and human BGLAP has been mapped to chromosome 1q, a region with homology to mouse Chromosome 3. It appears that BGLAP is the third calcium-binding protein that maps to human chromosome 1q and mouse Chromosome 3. |
