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Protein Coding Gene : Slc39a7 solute carrier family 39 (zinc transporter), member 7

Primary Identifier  MGI:95909 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  14977
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables zinc ion transmembrane transporter activity. Involved in B cell differentiation; skin epidermis development; and zinc ion transmembrane transport. Predicted to be located in endoplasmic reticulum membrane and nucleoplasm. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; immune system; and nervous system. Human ortholog(s) of this gene implicated in agammaglobulinemia 9. Orthologous to human SLC39A7 (solute carrier family 39 member 7).
PHENOTYPE: Mice homozygous for a conditional allele activated in intestinal epithelial cells exhibit premature death, loss of epithelial integrity, reduced enterocyte proliferation and increased enterocyte apoptosis. [provided by MGI curators]
  • synonyms:
  • MGI:2146797,
  • Ring5,
  • H2-K region expressed gene 4,
  • expressed sequence AL024048,
  • MGI:2146956,
  • AL024048,
  • expressed sequence AA408174,
  • AI117660,
  • Zip7,
  • expressed sequence AI117660,
  • MGI:2146748,
  • Slc39a7,
  • MGD-MRK-10505,
  • H2-Ke4,
  • solute carrier family 39 (zinc transporter), member 7,
  • Ke-4,
  • H-2K region expressed gene 4,
  • AA408174,
  • MGD-MRK-10394,
  • H-2Ke4,
  • KE4

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For